Marcola is an unincorporated community and census-designated place in Lane County, Oregon, United States. The community is located on the Mohawk River northeast of Springfield. The post office at this location was established in 1876 and originally called "Isabel" for early settler Isabel Applegate. In 1899-1900, a railroad was built through the Mohawk Va…Marcola is an unincorporated community and census-designated place in Lane County, Oregon, United States. The community is located on the Mohawk River northeast of Springfield. The post office at this location was established in 1876 and originally called "Isabel" for early settler Isabel Applegate. In 1899-1900, a railroad was built through the Mohawk Valley and a station named Marcola was established near the post office. Marcola was a name made up to honor Mary Cole, the wife of the town's founder, Columbus Cole. In 1901, the post office name was changed to agree with the name of the station.