Amide bonds are ubiquitous in pharmaceuticals, agrochemicals and biomolecules, and their formation underpins the synthesis of peptides, proteins and small-molecule therapeutics. Traditional chemical ...
A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl group (C=O) to a nitrogen atom. They're so ubiquitous that 117 of the top ...
Takeaway 3: The Alcohol-to-Amide Shortcut The team extended their logic to create a "one-pot" enzymatic cascade that starts from broadly available aliphatic alcohols. This chemoenzymatic strategy is ...
Researchers at the Biocatalysis group led by Dr Francesco Mutti at the Van ‘t Hoff Institute for Molecular Sciences (University of Amsterdam) have developed a novel use of alcohol dehydrogenase (ADH) ...
Extending or trimming the length of a drug molecule’s carbon backbone by just a couple of atoms can significantly alter its activity, even if nothing else in the structure changes. So reactions that ...
(4) Carboxylic acids and amines themselves do not react to form amides. Instead, a process activates the carboxylic acid, making it susceptible to amide formation. I don't get paid enough to broach ...
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Amide Technologies, a biotech that synthesizes challenging peptides, announced today that it has begun commercializing its novel peptide manufacturing platform. The ...
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Amide Technologies, a leading biotech company specializing in the synthesis of complex peptides, announced today the appointment of Dr. Brad Pentelute as its new CEO ...
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