US FDA pushes for new methods to replace animal testing in early drug studies

Food and Drug Administration on Wednesday issued a draft guidance to help companies reduce animal studies of experimental ...
Healio

FDA efforts to reduce animal testing signal shift toward AI, organ-on-chip study methods

In April 2025, the FDA announced plans to shift biomedical research for monoclonal antibodies and other medications away from animal testing toward new approaches. One year later, much speculation ...
MedPage Today on MSN

FDA Proposes More Flexibility in Alternatives to Animal Testing in Drug Development

Non-animal testing methods could save drugmakers time and money, officials say ...
Morning Overview on MSN

FDA urges alternatives to animal testing in early-stage drug development

The U.S. Food and Drug Administration is actively steering drug developers away from traditional animal studies and toward human-biology-based testing methods for monoclonal antibody programs. The ...
Applied Clinical Trials Online

FDA Issues Draft Guidance to Validate Non-Animal Testing Methods in Drug Development

The FDA has released a draft guidance outlining how drug developers can validate new approach methodologies (NAMs) as alternatives to animal testing in preclinical drug development. The guidance, ...

The age of animal experiments may be waning

Last November, the UK government announced a bold plan to phase out animal testing in some areas of research. Animal tests ...
Nature

How ‘animal methods bias’ is affecting research careers

While Catharine Krebs was working in a human-genetics laboratory during her PhD at the University of California, Los Angeles, there was a line that she got used to seeing at the end of papers: “These ...
WGAL

FDA says it will phase out animal testing requirement for monoclonal antibodies, drugs

The U.S. Food and Drug Administration announced Thursday that it will be phasing out a requirement that monoclonal antibodies and other drugs be tested on animals, saying in a news release that there ...
The Hill

Promising technologies are not yet ready to replace animal research

A recent op-ed in The Hill praising the National Institutes of Health’s new initiative to promote human-based technologies as a “major victory for animal ethics in science” oversimplifies a far more ...
STAT

There is no replacement (yet) for animal models in medical research

LaBonne is president of the Society for Developmental Biology and the Erastus Otis Haven professor of molecular biosciences at Northwestern University. Imagine a world without lifesaving medicines, ...