Patient-derived xenograft (PDX) models are emerging as a transformative tool in colorectal cancer (CRC) research, offering unparalleled insights into tumor biology, drug resistance, and personalized ...
Cancer remains one of the most pressing global health challenges, with millions of new diagnoses each year. While precision medicine and targeted therapies have transformed treatment strategies, many ...
Assessing risk of recurrence for nonmetastatic triple-negative breast cancer (TNBC) is a key determinant of therapeutic strategy. The best predictor of recurrence risk is failure to achieve a ...
The steps of establishing PDX models. With ongoing advancements in biobanking and artificial intelligence-driven drug discovery, PDX models are expected to become an indispensable tool in precision ...
Patient-derived xenografts (PDX) are preclinical models for precision cancer medicine. PDX models are highly recognized for recapitulating phenotype-genotype associations of their matched patient ...
Scientists have successfully developed a gastric cancer model using 3D bioprinting technology and patient-derived cancer tissue fragments. This innovative model preserves the characteristics of actual ...
Image Caption: Schematic overview of CRC PDX model establishment and propagation in immunodeficient mice. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and ...