For families of children with severe epilepsy, controlling seizures is often just the beginning of their challenges. Even in cases where powerful medications can reduce seizures, many children ...

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...

One of the challenges when studying brain development and disease is the limited access to live human brain tissue. Murine models have been extensively used to investigate brain development and ...

Researchers at the University of Maryland School of Medicine (UMSOM) have identified an innovation in stem cell therapy to regenerate neural cells in the brain after cardiac arrest in an animal model.

Advances in stem cell biology and tissue engineering have enabled the generation of brain organoids from human induced pluripotent stem cells (hiPSCs), providing powerful platforms to model human ...

Researchers at the University of Maryland School of Medicine (UMSOM) have identified an innovation in stem cell therapy to regenerate neural cells in the brain after cardiac arrest in an animal model.

While that provides a suitable model, Chanda and his team were interested in testing synapse properties in a human cellular environment that could eventually be more easily translated into treatments.

Neurons from grafted stem cells contain intrinsic codes for navigating and forming connections, which may improve cell therapy for a brain short-circuited by stroke. Some parts of our bodies bounce ...

Like the seeds of a forest, a few cells in embryos eventually sprout into an ecosystem of brain cells. Neurons get the most recognition for their computing power. But a host of other cells provides ...

The human brain can do many amazing things, but self-repair is not one of its repertoire of abilities. Once neurons die—from trauma, stroke, or disease—they rarely grow back. Scientists have been ...

A new 3D human brain tissue platform developed by MIT researchers is the first to integrate all major brain cell types, including neurons, glial cells and the vasculature into a single culture. Grown ...

A team of scientists—including Agnieszka Ciesielska (left), Barbara Klein (center), and Jeanne Paz (right)—showed that modified stem cells can improve brain activity, even when administered more than ...