Dynamic susceptibility contrast (DSC) MRI plays a pivotal role in the accurate diagnosis and prognosis of several neurovascular diseases, but is limited by its reliance on gadolinium, an ...

Systemic inflammation has been linked with major depressive episode (MDE) severity and treatment-resistant depression (TRD), but not for all patients. Brain mechanisms underlying these processes are ...

Investigators used MRI to evaluate brain perfusion in patients with transfusion-dependent (n=54) and non–transfusion-dependent (n=23) β-thalassemia versus 56 controls. They found that relative ...

A clinical study shows that preoperative dynamic susceptibility contrast (DSC) perfusion magnetic resonance imaging (MRI) can help predict how microbubbles will distribute in the human brain. This is ...

Brain scans reveal that metabolic health influences brain blood flow independently of age, with stronger cognitive effects in ...

Biologically speaking, there is no organ as vital or complex as the brain. And yet, the brain still remains somewhat a of a mystery-there’s a lot that even experts don’t know. Another troubling fact ...

The skull is so effective at protecting the brain that it has impeded the progress of neuroscience. In particular: A nice, thick skull poses challenges for imaging the brain in natural environments or ...

Two people of very different ages can have a similar level of biological aging in their brains. Such an occurrence is possible because aging and metabolic health follow two distinct pathways that ...