Cells from rapidly growing, highly metastatic tumors often contain numerous rings of extrachromosomal DNA (ecDNA). This ...

Experts from the University of Nottingham have discovered how a common genetic mutation disrupts the positioning of a key protein during cell division, revealing a new mechanism behind acute myeloid ...

The cells of higher organisms such as mammals, flies and fungi enclose their genetic material in a nucleus. A nuclear ...

The cell nucleus goes a long way during an immune response, both literally and figuratively. The white blood cells in question are cytotoxic T lymphocytes (CTLs), also known as killer T cells. These ...

Human genomic DNA is wrapped around core histone proteins to form nucleosomes, the fundamental units of chromatin. During ...

Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings of a new study by researchers at Linköping University in Sweden. The ...

Researchers have created an array of nanopillars that can breach the nucleus of a cell -- the compartment that houses our DNA -- without damaging the cell's outer membrane. This new 'gateway into the ...

Immune cells are the elite athletes of the human body. While other cells stay in place, immune cells travel throughout our bodies, squeezing through small channels, stretching themselves, sampling the ...

Newswise — Cornell University researchers have revealed a process that has stumped scientists for many years: exactly how an acid derived from vitamin A enters a cell's nucleus, where it has strong ...

Direct interactions between the cell’s powerhouses and nuclear pores might channel energy straight into the nucleus, fuelling cell division and differentiation. Menendez-Montes et al. investigated ...