Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment ...
To our immune system, a potentially lifesaving gene therapy can look a lot like a dangerous infection. That's because most genetic medicine uses viruses or double-stranded DNA to deliver genetic ...
Figure 1. Design and synthesis of circAMO . (a) Synthesis of a single-molecule ring by rigid regulation of selectivity; (b) Schematic diagram of circAMO design; (c) Synthesis of circAMO; (d) ...
A new scientific focus on extrachromosomal circular DNA (eccDNA) is opening transformative possibilities for disease detection, monitoring, and personalized medicine. Once considered a biological ...
Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...
Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...
A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues, the ...
Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes. Found exclusively in tumor cells, it often carries cancer-promoting genes (oncogenes) and is ...
The MarketWatch News Department was not involved in the creation of this content. CAMBRIDGE, Mass., March 11, 2026 /PRNewswire/ -- Full Circles Therapeutics today announced that its circular ...
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