Immune protection by the complement system depends on C3 cleavage by C3 convertases that is critical to all three activation pathways. Structural data on convertase formation in the classical pathway ...
It has been confirmed that the levels of immune proteins in the blood prior to antibody therapy in Alzheimer’s disease ...
Like their causative mutations, pathophysiology and natural history, the clinical presentation of inborn errors of immunity (IEI) varies widely. Nevertheless, some features, above all recurrent and/or ...