Dupuytren contracture is a disorder that can cause the fingers to curl in, primarily the ring and small fingers. It's a genetic condition mostly affecting men over 60 of Northern European descent.

Xiaflex (collagenase clostridium histolyticum) is a brand-name injection that’s prescribed for Peyronie’s disease and Dupuytren’s contracture in adults. As with other drugs, Xiaflex can cause side ...

We thank Drs Patrick, Farmer and Bromwich for their interest in our paper. In their letter they raised four main issues: contracture is not solely due to the loss of sarcomeres in muscles but also due ...