Zhijian “James” Chen received this year’s Albert Lasker Award for discovering cGAS, an enzyme which scopes out DNA-based ...
Deoxyribonucleic acid (DNA), and usually in the case of viruses ... On the other hand, STORM created better versions of four SARS-CoV-2 viral RNA sensors, improving their performance by up ...
CDCA7, whose mutations alter DNA methylation pattern and cause immunodeficiency, is a novel sensor for a special class of methylated DNA. DNA methylation is a process in which a methyl group is ...
However, in the half-century since the structure of DNA was first elaborated ... called riboswitches (or RNA switches). Riboswitches are RNA sensors that detect and respond to environmental ...
A new study in Nature identifies a long-sought cytoplasmic 'sensor' that is responsible, at least in part, for interferon responses induced by double-stranded DNA. How do cells detect non-self ...
Mice express full-length protein ZBP1-L as well as an alternatively-spliced shorter isoform (ZBP1-S) containing only its two ...
Transmembrane β-barrel pores (TMBs) are extensively used for single-molecule DNA and RNA sequencing ... current approaches to ...
Theory, development, and applications of biochemical sensors used in medical diagnosis and patient ... with a focus on detection of biomolecules (e.g., DNA, RNA, proteins, metabolites), enzyme ...
Ultraviolet radiation in the shortest wavelength band breaks down DNA and RNA, so it’s a great way ... It is built around a $2.50 sensor and a $3 Arduino. The NukeMeter is built around a GUVA ...
These nucleotides can then be further processed to form the pyrimidine bases found in DNA and RNA. The pyrimidine biosynthetic pathway ... such as molecular machines, sensors, and catalysts. The ...
“For these sensors to detect hemimethylation, they must directly and selectively bind the hemimethylated DNA substrate,” Wassing says. “CDCA7 seems uniquely able to do that while the DNA is ...
For this reason, maintenance of the DNA methylation pattern is important to ensure the correct and consistent function of each cell type. But this is no easy feat: the DNA methylation pattern can ...