Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, No. 4 (January 27, 2015), pp. 971-976 (6 pages) Filamentous phage are elongated semiflexible ssDNA viruses ...
New insights into the structure of phages will enable researchers to develop new uses for the viruses in biotechnology. Phages are viruses that infect bacteria, which enables them to be exploited as ...
Bacteriophages, or phages for short, are viruses that infect bacteria. Using phages therapeutically could be very useful in fighting antibiotic-resistant pathogens, but the molecular interactions ...
For the first time, researchers at the University of Exeter, in collaboration with Massey University and Nanophage Technologies, have mapped out what a commonly-used form of phage looks like. Their ...
A hybrid bacteriophage, P420, was constructed in vitro; it contains part of bacteriophage P4 and a 3.6-kilobase derivative of plasmid ColE1. In Escherichia coli, the plasmid-phage hybrid can exist as ...
BioRxiv (2023) PubMed PMID: 37546940; PubMed Central PMCID: PMC10402079. The mammalian innate immune system uses cyclic GMP–AMP synthase (cGAS) to synthesize the cyclic dinucleotide 2′,3′-cGAMP during ...
Bacteria use antiphage systems to combat phages, their ubiquitous competitors, and evolve new defenses through repeated reshuffling of basic functional units into novel reformulations. A common theme ...
Recent studies reported the design of a new generation of phage-based particles for targeted systemic gene delivery, which consist of the packaging of a recombinant rAAV2 DNA by coat proteins of a ...
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