A cell model that replicates the structure and function of the human intestine has been developed, creating an evaluation platform capable of more accurately predicting adverse effects of new drugs.

The mammary gland is remarkable in its capacity to undergo multiple cycles of growth and regression during reproductive years. Mammary gland remodeling is largely driven by hormonal cues that guide ...

Alterations in intestinal structure, mechanics and physiology underlie acute and chronic intestinal conditions, many of which are influenced by dysregulation of microbiome, peristalsis, stroma or ...

A new comprehensive atlas of cells fills gaps in knowledge on how different cells in the intestine act together to drive celiac disease, potentially opening new avenues for future therapeutic ...

A new preclinical study from Weill Cornell Medicine found that the protein caspase-5 (CASP5), long thought to be a foot soldier in the body's defense against bacterial infection, does not actually ...

Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation ...

Coeliac disease is a long-term autoimmune condition that affects about 0.5% to 1% of people. A new published collaborative report from scientists at Children’s Health Ireland (CHI) , Johnson & Johnson ...

Animal models have enabled us to learn an incredible amount of new information about human biology, health, and disease. But these animals can't always serve as a reliable example of the human body.

In a recent study published in the journal Frontiers in Immunology, researchers investigate the impact of dietary antigens in regulating small intestinal tumors. Despite being the most common type of ...