A new meta-analysis shows meaningful differences among FDA-approved antipsychotic adjuncts for MDD, with lumateperone showing the strongest efficacy and aripiprazole the best overall acceptability.

HealthDay News — Treatment with semaglutide significantly improves measures of motivation in patients with major depressive disorder (MDD), according to a study published April 29 in JAMA Psychiatry.

(Hinterhaus Productions/Getty Images Plus) Cannabis use disorder has been strongly linked with major depressive disorder in a ...

Many people with major depressive disorder get no relief from current treatments. Newer combinations of existing medications ...

While they share similar depressive and cognitive symptoms, the biological underpinnings of bipolar disorder and major ...

A new study uses real-time fMRI neurofeedback to help depression patients reduce rumination by training specific brain circuits in a gamified environment.

Anhedonia reduces the ability to feel joy and affects nearly 90% of people with major depression. Most conventional therapies ...

Patients with chronic conditions who are failing on conventional therapies may be suffering from undiagnosed major depression ...

Ketamine, a common anesthetic, is being used in Maryland to help people with major depression.About 48 million U.S. adults ...

Auvelity is a medicine for major depressive disorder, commonly known as depression. It was approved by the FDA in 2022. It is an oral tablet that contains a combination of two medicines called ...

Nearly 1 in 5 U.S. adolescents experienced depression between 2021 and 2023, and those teens were significantly more likely ...

Psychotherapy is the intervention of first choice, and pharmacotherapy can be considered when psychotherapy alone is not ...