A study published in the Journal of Neuroscience sheds new light on how brain cells relay critical information from their extremities to their nucleus, leading to the activation of genes essential for ...

The human brain is known to store various memories for long periods of time, progressively learning from new experiences and forming adaptive representations that ultimately guide decision-making and ...

When a new memory forms the brain undergoes physical and functional changes known collectively as a “memory trace.” This memory trace represents the specific patterns of neuronal activity and ...

Associative memories are gradually embedded within neocortical circuits during systems-level memory consolidation, the process by which remote memories acquire stability and persistence over time 1,2.

In an important study for understanding how memories are made, cientists show that the flexibility of chromatin -- packaged DNA inside the cell -- plays a crucial role in 'deciding' which neurons are ...

Computational models show that even subtle modifications in the synaptic protein CaMKII completely alter the resulting protein structures. Given how the formation and stability of these structures ...

Synaptic connections between neurons determine the flow of information in the brain. Changes in synaptic weight, along with synapse formation and pruning, reshape the functional connectivity of neural ...

Researchers from Kyushu University discovered a previously unrecognized synaptic "hotspot" that forms during adolescence, challenging the long-held view that adolescent brain development was dominated ...

In a study supported by the National Institutes of Health (NIH), researchers revealed the structural underpinnings of memory formation across a broad network of neurons in the mouse brain. This work ...

Neurons have variable levels of chromatin compaction, shown as different shades of red. The less compact a neuron, the more likely it is to be recruited into the memory trace (green). When we form a ...