University of Wollongong (UOW) scientists have developed a breakthrough therapy that clears toxic proteins from nerve cells—a ...

A drug candidate found to protect nerve cells damaged by motor neuron disease (MND), could offer new hope to people living ...

For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside ...

Researchers have shown that hundreds of proteins and mRNA molecules are found in the wrong place in nerve cells affected by Motor Neuron Disease (MND), also known as Amyotrophic Lateral Sclerosis (ALS ...

The paper, “ Intrinsically accelerated cellular degradation is amplified by TDP-43 loss in ALS-vulnerable motor neurons in a zebrafish model ,” suggests that the cellular degradation load linked to ...

Once a concept saved for science fiction and superheroes, progress in the gene therapy field has brought human DNA modification into the realm of reality. Researchers have made tremendous ...

Motor neuron diseases, such as amyotrophic lateral sclerosis (ALS) and hereditary spastic paraplegia (HSP), share physical similarities but have been largely viewed as genetically distinct. However, ...

Blocking a small RNA molecule called miR-140-3b can improve motor function in a mouse model of SMA, a study suggests.

Noise as loud as 85 to 100 decibels over time led to irreversible motor defects and loss of dopamine neurons in a mouse model ...