The NFL Week 6 schedule could be full of close, intense games. It is full of intriguing betting lines. What do NFL betting odds say about each game this week, the sixth week of the 2025 NFL regular season? Arizona State's 1975 football team earns overdue ...

The Chiefs are back in the top three after a win on Sunday over the Lions, who moved down slightly from +800 to +850. Kansas City is now +700 after having a +1000 price last week. The Eagles didn't drop much, going from +700 to +950 after a loss to the Giants to open Week 6. The big moves have come in the middle of the pack.

However, if the Titans do stuff the box, Daniel Jones and the passing offense will light them up since they also rank dead last in defending quick passes in the NFL. It will be a long Sunday for the Titans, and the Colts will likely find themselves around 40+ points again.

Atlanta Falcons vs Buffalo Bills picks, predictions, odds, win probabilities for NFL Week 6 Monday Night Football game on Oct. 13. Who will win game?

Looking for upsets? More than one team overcame the odds in Week 6 of the 2025 NFL season. Find out more about those underdogs who came out on top in the article below. FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Three more teams — the Eagles, Rams, and Buccaneers — have odds of 7/1 or better. Further down the list, the 49ers, Commander,s and Seahawks are all 12/1 or better. Dylan Svoboda is a versatile writer and analyst across many sports. He’s particularly knowledgeable about the big three — MLB, the NFL and the NBA.

Sunday's NFL Week 7 action kicked off early in London with the Los Angeles Rams facing the Jacksonville Jaguars at a rainy Wembley Stadium in the league's fourth straight international game. Jaguars coach Liam Coen expressed frustration and took blame after the Jaguars' 35-7 loss to the Rams (5-2),