Engineered lipid nanoparticles reprogram immune metabolism for better mRNA vaccines

The most common side effects of mRNA vaccines like the COVID-19 shot are well known: soreness, mild fever, and general ...

Sometimes less is more: Messier nanoparticles may actually deliver drugs more effectively than tightly packed ones

The tiny fatty capsules that deliver COVID-19 mRNA vaccines into billions of arms may work better when they're a little disorganized. That's the surprising finding from researchers who developed a new ...

Simple 'cocktail' of amino acids dramatically boosts power of mRNA therapies and CRISPR gene editing

Lipid nanoparticles, or LNPs, best known as the delivery vehicle for the COVID-19 mRNA vaccines received by billions of ...

Scientists Discover Simple Trick That Boosts mRNA Therapy Delivery 20-Fold

Lipid nanoparticles, or LNPs, are best known as the delivery system used in the COVID-19 mRNA vaccines given to billions of ...
The Scientist

Three Amino Acids Improve Lipid Nanoparticle Therapy Delivery to Cells

Increasing the efficiency of LNPs as therapeutic vehicles offers promise for better mRNA-based and gene editing treatment ...

Robotic microfluidic platform brings AI to lipid nanoparticle design

AI has designed candidate drugs for antibiotic-resistant infections and genetic diseases. But efforts to incorporate AI into ...