Common OTC painkillers like ibuprofen may increase heart attack and stroke risk. Learn which medications pose the greatest cardiovascular danger.

Dr. Portenoy answers the question: 'Over-The-Counter Pain Relievers Harmful?' — -- Question: Can Over-The-Counter Pain Relievers Be Harmful, And Are They Safer Than Other Drugs (Narcotics)?

Over-the-counter (OTC) pain medications are generally safe and effective, but daily or long-term use isn’t recommended. Several factors, including drug side effects and your medical history, can ...

This story was originally published on April 18, 2025, and has been updated. On Monday, President Trump announced that the Food and Drug Administration would be discouraging the use of acetaminophen ...

Dr. Portenoy answers the question: 'Over-The-Counter Pain Killers, Caffeine?' — -- Question: Why Do Some Over-The-Counter Pain Killers Contain Caffeine, And Is That A Good Thing? Answer: Another ...

Migraine is a common brain disease of recurrent attacks of moderate to severe head pain that can worsen with movement and can come with associated symptoms of nausea and/or vomiting and/or light and ...

When hit with a headache or fever, people often reach for over-the-counter painkillers like acetaminophen or nonsteroidal anti-inflammatory drugs (NSAIDs) as their first line of defense. Used ...

Everyday Health independently vets all recommended products. If you purchase a featured product, we may be compensated. Learn why you can trust us. Everyday Health independently vets all recommended ...

Over-the-counter (OTC) pain medications were as, or more effective, than prescription opioids at relieving dental pain after wisdom tooth extraction, new research showed. The pain relief was ...

If you’ve ever walked away from a tough workout with the poise of an immortal gladiator, only to wake up two days later feeling like you’ve been run over by a horse-drawn chariot, you’ve experienced ...

When hit with a headache or fever, people often reach for over-the-counter painkillers like acetaminophen or nonsteroidal anti-inflammatory drugs (NSAIDs) as their first line of defense. Used ...