The PI3K/Akt pathway plays a central role in cancer progression by regulating cell proliferation, survival, and metabolism. Dysregulation of this pathway, often due to mutations in genes such as ...
The alternative text for this image may have been generated using AI. Non-clinical studies have provided important insights into the complexity and redundancy of the PAM pathway and have identified ...
Reversible epigenetic control of CD146 phenotypic states in MDA-MB-231 breast cancer cells. Real-world outcomes in patients (pts) with metastatic breast cancer (MBC) treated with trastuzumab ...
This is an ASCO Meeting Abstract from the 2026 ASCO Annual Meeting I. This abstract does not include a full text component.
Low-dose aspirin significantly reduced colorectal cancer recurrence in patients with PI3K pathway gene alterations, nearly halving recurrence rates over three years compared to placebo. The study ...
A team of researchers from the Badalona Applied Research Group in Oncology (B·ARGO) and the Urologic Tumours Unit of the Institut Català d'Oncologia (ICO) and the Germans Trias i Pujol Research ...