The body's organs are in constant communication. Fat tissue tells the liver when to store or release energy, the immune ...

Imaging-based methods are widely used for studying the subcellular localization of proteins in living cells. While routine for individual proteins, global monitoring of protein dynamics following ...

By combining CRISPR knock-in with small peptide tags, researchers can study proteins in their native cellular context, ...

CAMBRIDGE, England--(BUSINESS WIRE)--Abselion, a pioneering life sciences technology company focused on simplifying biomolecule quantification, has expanded its Amperia™ assay portfolio with the ...

The overexpression of many recombinant proteins can lead to improper folding, in vivo degradation, or their sequestration in insoluble inclusion bodies, all of which result in low yields of soluble ...

Scientists at La Trobe University have created a world-first method to investigate "disordered" proteins in living cells, in research that could change how we understand and treat Parkinson's disease.

Healthy cells are constantly breaking down proteins and building up new ones with the help of enzymes aptly named unfoldases, because they unravel proteins tagged for destruction or recycling. Now, a ...

His-tagged proteins are central to assay development, structural biology, and drug discovery projects. Their small tag facilitates rapid construct iteration and straightforward purification. Teams ...

Rush hour never ceases at the nucleus’ border. Gene products begin their lives in the nucleus as strands of mRNA that ship out into the cytoplasm, where they serve as templates for protein synthesis.

Three dimensional cryo-EM structure of VCP (blue and purple) bound to three VCPIP1 promoters (red, orange, and yellow). Healthy cells are constantly breaking down proteins and building up new ones ...