The excessive production of reactive oxygen species (ROS) can lead to single nucleic acid base damage, DNA strand breakage, inter- and intra-strand cross-linking of nucleic acids, and protein-DNA ...
Guanine-rich DNAs can fold into noncanonical DNA structures called G-quadruplexes (G4s). G4s are formed by the stacking of several G-tetrads, each of which consists of four guanine bases held together ...
DNA, the genetic material compacted in chromosomes, stores information to regulate all the cell processes in the body. Two decades ago, in addition to the widely known Watson-Crick double helix model ...