The first place you need to look to understand “chirality” are your hands – identical structures that cannot be successfully superimposed over one another. Like our hands, many molecules also exhibit ...

In recent years, industrial biocatalysis has significantly advanced, largely due to innovations in DNA sequencing, bioinformatics, and protein engineering. However, the challenge of implementing ...

In conventional solid-phase peptide synthesis (SPPS), α-amino groups are protected with alkoxycarbonyl groups (e.g., 9-fluorenylmethoxycarbonyl [Fmoc]). However, during SPPS, inherent side reactions ...

Pharmaceutical process chemists use resolutions, or the separation of enantiomers from racemic mixtures, more than 60% of the time to generate chiral compounds. Among resolution methods, ...