In the mammalian kidney renal medullary cells use organic osmolytes such as sorbitol, myo-inositol, glycerophosphorylcholine, betaine, and taurine to adjust their intracellular osmolarity (and thereby ...

Augusta, GA) – In human diabetic patients, an excessive vasoconstrictive and pro-aggregatory thromboxane (TXA2) renal synthesis, along with a decrease in vasodilatory and anti-aggregatory ...

Constancy of the milieu intérieur, defined by Claude Bernard in the late 1800s, is essential for terrestrial life. Sodium balance in humans is part and parcel of that environment and is maintained in ...

A prospective trial assessing the effects of clamp ischemia during partial nephrectomy on renal function, biomarkers, and structure. Background: Although the von Hippel-Lindau (VHL) tumor suppressor ...