In a study published in Current Biology on August 14, Prof. Miao Wei's team at the Institute of Hydrobiology (IHB) of the Chinese Academy of Sciences and Prof. Zhang Jianzhi's team at the University ...
After manual review and curation, 27 candidate variants met criteria for pathogenic or likely pathogenic variants, from 21 different cyst samples, and were flagged for further statistical analysis ...
Colorectal tumors that underwent somatic next-generation sequencing (NGS) for 154-168 genes in an in-house laboratory between 2015 and 2022 were retrospectively identified. Microsatellite instability ...
Somatic mutations are changes to the DNA sequence that arise in non-reproductive cells during a plant’s lifetime, generating genetic mosaicism within leaves, stems and roots. In plants, the absence of ...
In this Innovation Spotlight, Peter Campbell, the cofounder and chief scientific officer of Quotient Therapeutics discusses a new somatic genomics platform built to identify these mutations and ...
The COSMIC Knowledgebase, the world’s leading expert-curated resource for somatic mutations in cancer, combines rigorous ...
Two new studies from Karolinska Institutet in Sweden have investigated how mutations that occur in muscles and blood vessels over time can affect aging. The studies, which are published in Nature ...
New research suggests that autoimmune diseases may be driven by DNA mutations in immune cells that remove the natural brakes on the immune system. It reveals a previously hidden role for somatic ...
A pivotal study has provided unprecedented insights into the genetic architecture of sweet oranges, highlighting the critical role of somatic mutations in shaping fruit development. By constructing a ...
From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body's typically efficient DNA repair machinery and potentially affecting our health ...
As I am writing this, my DNA is changing. And, as you read this, so is yours. People tend to assume that the genes we inherit from our parents are a fixed blueprint for our growth and development, ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results