C5aR1 expression correlates with increased metastasis risk and poor survival in cSCC patients. The tumor microenvironment, especially fibroblasts, influences C5aR1 expression and cSCC progression.

Schlesinger: For advanced cSCC, immunotherapy has been a game-changer. The first immunotherapy drugs approved in the space were PD-1 inhibitors such as cemiplimab (Libtayo; Regeneron) and ...

Comparing metagenomic profiles of the skin microbiome in immunosuppressed patients and those at high and low risk for cutaneous squamous cell carcinoma (SCC) revealed distinct expansions in fungal and ...

Mohs surgery was associated with improved outcomes compared with wide local excision (WLE) in patients with primary high-stage cutaneous squamous cell carcinoma (cSCC), showing lower rates of ...

Extreme heat and plenty of sunshine is a given for Atlanta, especially this summer. In June, there were nearly 285 hours of sunshine, and we’re on track for more rays this month, according to U.S.

There are three common types of skin cancer in the United States: basal cell carcinoma, squamous cell carcinoma and melanoma. Merkel cell carcinoma is a rare type of skin cancer. Fred Hutch Cancer ...

Personal cancer journey emphasizes the emotional and physical challenges faced by patients during diagnosis and treatment. Patient advocacy is crucial in navigating the healthcare system and making ...