In the Alzheimer’s disease brain, synaptic loss correlates with cognitive decline, and is considered a sign of disease progression. But is synaptic loss always bad? Provocative new data from several ...

A research group led by Kazunobu Sawamoto, a professor at Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences and National Institute for Physiological Sciences, and ...

Long-term use of benzodiazepines, commonly prescribed for anxiety and insomnia, may impair cognition and increase the risk of developing dementia. How? By activating microglia to prune synapses, ...

Francesca has an MSci in Biochemistry from the University of Birmingham.View full profile Francesca has an MSci in Biochemistry from the University of Birmingham. Use it or lose it – that’s the motto ...

Researchers led by a group at the Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences and the Nagoya City University School of Medicine report that they have shed ...

Researchers have shown in mice how immune cells in the brain target and remove unused connections between brain cells during normal development. This research, supported by the National Institutes of ...

A multidisciplinary team of scientists has discovered the mechanism that controls synaptic pruning of new neurons in the adult brain. The team discovered that microglial cells control the number of ...

The poor function of microglia, the brain's immune cells in individuals exposed to early life adversity (ELA) promotes aberrant responses to stress in adulthood that may be linked to mental illness, ...

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition in which affected individuals experience difficulties in social communication and exhibit restricted, repetitive patterns of ...