Co-written with Jai Liester. Silent synapses represent one of neuroscience's most fascinating discoveries—connections between neurons that lie dormant until activated by specific triggers. These ...

Long-term use of benzodiazepines, commonly prescribed for anxiety and insomnia, may impair cognition and increase the risk of developing dementia. How? By activating microglia to prune synapses, ...

Does ApoE4, the strongest genetic risk factor for sporadic Alzheimer’s, prevent synaptic pruning? Counterintuitively, that is what scientists conclude in the September 6 Proceedings of the National ...