Receptors are specialised membrane‐bound proteins that play a fundamental role in translating extracellular signals into precise intracellular responses. Integral to cellular communication, these ...
Glucocorticoid receptors (GRs) are ligand-activated transcription factors that play a pivotal role in mediating the effects of endogenous and synthetic glucocorticoids. These receptors regulate a ...
Humans have about 400 odorant receptors (ORs), but scientists have had trouble finding ligands that match up with most of ...
Edited by Karen Young Kreeger J.A. Bennett, R. Dingledine, "Topology profile for a glutamate receptor: Three transmembrane domains and a channel-lining reentrant membrane loop," Neuron, 14:373-84, ...
Although scientists can learn a lot from cell culture and animal models, they cannot truly substitute for all parts of the human body, especially the brain. But scientists have now used human brain ...
Phase I Evaluation of Prolonged-Infusion Gemcitabine With Irinotecan for Relapsed or Refractory Leukemia or Lymphoma ABSTRACT: Androgen receptor (AR) is a member of the steroid hormone receptor family ...
Turning a decades-old dogma on its head, new research from scientists at UC San Francisco and Stanford Medicine shows that the receptor for oxytocin, a hormone considered essential to forming social ...
Biology Of Neoplasia October 20, 2005 Biology of Progesterone Receptor Loss in Breast Cancer and Its Implications for Endocrine Therapy Authors: Xiaojiang Cui, Rachel Schiff, Grazia Arpino, C. Kent ...
A cell’s ability to react to its surroundings is one of its fundamental roles. Therefore, it makes sense that one of the ...
New research is changing what we thought we knew about a common brain receptor in the brain. Glutamate receptors modulate most of the excitatory neural activity in the central nervous system. The ...
October is Breast Cancer Awareness Month, and CURE is here to address some of the most common questions patients have after a breast cancer diagnosis. October is Breast Cancer Awareness Month, a time ...