Glucocorticoid receptors (GRs) are ligand-activated transcription factors that play a pivotal role in mediating the effects of endogenous and synthetic glucocorticoids. These receptors regulate a ...
Humans have about 400 odorant receptors (ORs), but scientists have had trouble finding ligands that match up with most of ...
T cell receptors (TCRs) are fundamental to the adaptive immune system, playing a pivotal role in recognising and responding to pathogenic challenges. Generated through the process of V(D)J ...
An international research team led by a University of Ottawa Faculty of Medicine investigator has revealed ultra-detailed ...
Edited by Karen Young Kreeger J.A. Bennett, R. Dingledine, "Topology profile for a glutamate receptor: Three transmembrane domains and a channel-lining reentrant membrane loop," Neuron, 14:373-84, ...
Although scientists can learn a lot from cell culture and animal models, they cannot truly substitute for all parts of the human body, especially the brain. But scientists have now used human brain ...
Turning a decades-old dogma on its head, new research from scientists at UC San Francisco and Stanford Medicine shows that the receptor for oxytocin, a hormone considered essential to forming social ...
Phase I Evaluation of Prolonged-Infusion Gemcitabine With Irinotecan for Relapsed or Refractory Leukemia or Lymphoma ABSTRACT: Androgen receptor (AR) is a member of the steroid hormone receptor family ...
Biology Of Neoplasia October 20, 2005 Biology of Progesterone Receptor Loss in Breast Cancer and Its Implications for Endocrine Therapy Authors: Xiaojiang Cui, Rachel Schiff, Grazia Arpino, C. Kent ...
New research is changing what we thought we knew about a common brain receptor in the brain. Glutamate receptors modulate most of the excitatory neural activity in the central nervous system. The ...
October is Breast Cancer Awareness Month, and CURE is here to address some of the most common questions patients have after a breast cancer diagnosis. October is Breast Cancer Awareness Month, a time ...