Parabilis Medicines, a clinical-stage biopharmaceutical company committed to creating extraordinary medicines for people ...

A Wnt/β-catenin pathway agonist under development by Surrozen appears to be effective against idiopathic pulmonary fibrosis (IPF) in mouse models, according to new data. The results, published April 2 ...

Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...

Randomized, double blind, phase II trial: Epigenetic therapy (valproic acid and hydralazine) plus chemotherapy versus placebo plus neoadjuvant chemotherapy in operable and locally advanced breast ...

A new study finds that hair turns grey when pigment stem cells get trapped inside follicles instead of moving to the ...

A comprehensive, multi-phase investigation published in Advanced Science suggests that the amino acid tryptophan (Trp) may be a key determinant of therapeutic response to conventional synthetic ...

Tiny gold particles that act as carriers for lithium can be delivered directly to the brain in the form of a nasal spray.

The team from the Institute of Science Tokyo, used genetically modified mice and lineage-tracing techniques to shed light on the cell signaling mechanisms ...