The Buffalo Bills have waited years for this moment. Now they’re back, and facing a familiar foe. Once again the fate of the AFC hinges on a game between the Bills and Chiefs, but this is the first time since 2021 that they’ve met in the Championship game.

For the second time since the 2024-25 regular season began, the Kansas City Chiefs will face the Buffalo Bills in a matchup between two of the NFL's most exciting teams. This time around, however, there's a trip to Super Bowl LIX hanging in the balance.

We break down the biggest strengths and question marks in the Bills-Chiefs matchup, plus the X-factors that could make all the difference.