State police responded to the crash around 11 p.m. Monday near the 218-mile marker of southbound I-65.

At least one person is dead after multiple semis crashed and caught on fire on Interstate 65 in Jasper County Monday night.

N ASHVILLE, Tenn. (WSMV) - Several lanes of Interstate 65 North are shut down due to a crash at mile marker 72 just north of ...

Man dies in motorcycle collision on Interstate 65 in Nashville; another rider injured, tractor-trailer involved.

A Gary man was killed on Interstate 65 late Saturday night when he was struck by another vehicle while trying to put fuel in ...

Police believe Daryus Chambers, 37, crashed into a tractor-trailer and then was run over by another motorcyclist.

Southbound I-65 in southeast Indianapolis will close this weekend as crews continue progress on drainage improvements beneath the interstate. Southbound I-65 is scheduled to close at 9 p.m. on Friday ...

The Greenwood Fire Department has confirmed that one person died in a plane crash a mile away from the Indy South Greenwood ...

A section of Interstate 65 in Louisville will be closed for more than a month, officials said. Southbound lanes of the highway closed Tuesday night at the John F. Kennedy Memorial Bridge and will ...

A single-vehicle crash on Interstate 65 has led to a complete road closure near mile marker 306. The incident occurred at ...

Nearly a year after a member of a Tennessee Department of Transportation trash pickup crew was hit along Interstate 65, ...

A 55-year-old woman was fatally struck by a vehicle in a hit-and-run incident early Monday morning. The Birmingham Police ...