RMD Open

Impaired cardiorespiratory fitness in psoriatic arthritis: insights from cardiopulmonary exercise testing

Background Data on cardiorespiratory fitness (CRF) in psoriatic arthritis (PsA) are scarce. This study aimed to determine the ...
RMD Open

Rheumatic and musculoskeletal disorders in musicians: risks, adaptations and management

Music therapy is recognised as a complementary or alternative therapy for osteoarthritis and fibromyalgia, but playing music can have health repercussions for musicians in the field of ...
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Correction: Hydroxychloroquine and pregnancy outcomes in patients with anti-phospholipid syndrome: a systematic review and meta-analysis

Berman A, Kenet G, Lubetsky A, et al. Hydroxychloroquine and pregnancy outcomes in patients with anti-phospholipid syndrome: a systematic review and meta-analysis ...
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Systematic review and network meta-analysis of the efficacy and safety of tumour necrosis factor inhibitor–methotrexate combination therapy versus triple therapy in ...

Objective Clinical trials have not consistently demonstrated differences between tumour necrosis factor inhibitor (TNFi) plus methotrexate and triple therapy (methotrexate plus hydroxychloroquine plus ...
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Glucocorticoids and chronotherapy in rheumatoid arthritis

It is evident that the morning symptoms of rheumatoid arthritis (RA) are linked to the circadian abnormal increase in night inflammation, favoured by inadequate cortisol secretion under conditions of ...
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Accuracy of musculoskeletal imaging for the diagnosis of polymyalgia rheumatica: systematic review

Methods Searches included MEDLINE, EMBASE and PubMed. Evaluations of diagnostic accuracy of imaging tests for PMR were eligible, excluding reports with <10 PMR cases. Two authors independently ...
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Validating 10-joint juvenile arthritis disease activity score cut-offs for disease activity levels in non-systemic juvenile idiopathic arthritis

Objectives To validate cut-offs of the Juvenile Arthritis Disease Activity Score 10 (JADAS10) and clinical JADAS10 (cJADAS10) and to compare them with other patient cohorts. Methods In a national ...
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Systematic literature review informing the 2022 update of the EULAR recommendations for the management of ANCA-associated vasculitis (AAV): Part 2 - Treatment of eosinophilic ...

Objective To summarise and update evidence to inform the 2022 update of the European Alliance of Associations of Rheumatology (EULAR) recommendations for the management of antineutrophil cytoplasmic ...
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Prospective study of complications and sequelae of glucocorticoid therapy in ANCA-associated vasculitis

Objective Glucocorticoids (GC) are a cornerstone in treating antineutrophil cytoplasmic antibodies-associated vasculitides (AAV), however, they add to morbidity and mortality. To date, GC toxicity in ...
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Multiple DMARD discontinuations in rheumatoid arthritis: how often and in what patients? Results from a national clinical RA register

Objectives Multiple discontinuations of biologic (b-) or targeted synthetic (ts-) disease-modifying antirheumatic drugs (DMARDs) may indicate difficult-to-treat disease. We aimed to assess the ...
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Possibilities for personalised medicine in rheumatoid arthritis: hype or hope

Knowledge of pathophysiology of rheumatoid arthritis (RA) has improved over the past decades, which resulted in new treatment options and strategies that led to better clinical outcomes. At the same ...
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Disease modification achievement in patients with lupus nephritis in a real-life setting: mission impossible?

Objective A preliminary definition of disease modification (DM) in lupus nephritis (LN) was recently developed focusing on long-term remission and damage prevention, with minimal treatment-associated ...