Nucleophilic substitution reactions remain a cornerstone of organic chemistry, offering a window into the fundamental aspects of reactivity and selectivity in molecular transformations. At the heart ...

Scientists have been naming ideas, theorems, discoveries, and so on after other scientists for a very long time (Newton’s laws of motion, anyone?). Chemists are no different. They’ve been naming ...

Making molecules with quaternary carbon bonds—four carbons attached to a central C—is tricky but necessary for medicinal chemists. Quaternary C bonds have a discrete shape, Princeton University ...