Jones had both the highest completion percentage (69.6 percent) and yards per attempt (7.4) of his career during that stretch ...

The last time the Colts and 49ers played was in the 2021 season, when the Colts defeated San Francisco on the road by a score ...

The Indianapolis Colts will enter their Monday Night matchup against the San Francisco 49ers as the home underdogs. At 8-6 on ...

An ESPN analyst believes the 49ers can make noise in the playoffs, but one fatal flaw could derail San Francisco's postseason ...

The 49ers' playoff picture will be dramatically impacted by tonight's NFC West battle in Seattle between the Seahawks and ...

One prominent NFL insider named two teams that could potentially be interested in trading for San Francisco 49ers QB Mac ...

Which team will win the NFL Week 16 game on Monday Night Football? Check out these NFL Week 16 picks and NFL Week 16 predictions for the game, which can be seen at 6:15 p.m. MST on ESPN ...

ESPN's Field Yates shared his first-round prediction for the San Francisco 49ers in a way-too-early 2026 NFL mock draft.

ESPN announced a major change for the Week 16 showdown between the San Francisco 49ers and Indianapolis Colts.

As the Indianapolis Colts look to keep their playoff hopes alive, up next for them is a home matchup with the San Francisco ...

Despite losing to the Seattle Seahawks on Sunday in his first start since the 2020 season, Indianapolis Colts veteran ...

The San Francisco 49ers got a crucial update on former first-round WR Ricky Pearsall's injury status, courtesy of HC Kyle Shanahan.