Background Advances in systemic therapy for advanced hepatocellular carcinoma (HCC) have fuelled a growing interest in ...

Metastatic pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest solid cancers, portending poor patient outcomes ...

Background Translating microbiome correlations into robust predictive features for complex gut disorders remains elusive, ...

Background Engineered bacterial therapeutics represent a promising strategy for sustained intestinal delivery of therapeutic ...

Background Programmed death ligand 1 (PD-L1) blockade offers new therapeutic options for oesophageal squamous cell carcinoma ...

Background Pain in chronic pancreatitis (CP) is multifactorial. Efficacy of pancreatic enzyme replacement therapy (PERT) for pain remains uncertain. Objective To assess the effect of ...

Department of Psychosomatic Medicine, Kyushu University, Fukuoka, Japan. Fifty nine patients admitted with a diagnosis of psychogenic vomiting were classified into five patterns of vomiting: ...

1 Department of Gastroenterology, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai, China 2 International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary ...

The Rome diagnostic criteria for the functional bowel disorders and functional abdominal pain are used widely in research and practice. A committee consensus approach, including criticism from ...

Objective Mutations in presenilin genes are the major cause of Alzheimer’s disease. However, little is known about their expression and function in the gut. In this study, we identify the presenilins ...

Refractory coeliac disease (RCD) is defined by persistent or recurrent malabsorptive symptoms and villous atrophy despite strict adherence to a gluten-free diet (GFD) for at least 6–12 months in the ...

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