In a New Game+ in Dead Space Remake, you may stumble upon marker fragments. There are 12 marker fragments and if you collect them all before Chapter 12 begins, you can unlock a secret, alternate ...

We talked to Brit Barnes, who has turned screws and fixed skis at Big Sky for more than a decade. Recommended, factory recommended, freeride, backcountry—it can be a headache even for shop guys. Where ...

Complete your on-mountain kit with this selection of ski accessories, including protection, eyewear, poles, boot warmers and tuning equipment. Getting kitted out for ski season isn’t just about ...

Mismatch repair pathway is frequently dysregulated across cancer types, commonly represented by loss of MLH1 or MSH2 gene expression. Here the authors model MLH1 missense mutations from patients to ...