The last time the Colts and 49ers played was in the 2021 season, when the Colts defeated San Francisco on the road by a score ...

Week 16 features huge matchups with the NFL playoffs approaching. Here are the odds, spreads and totals for every game.

As the Indianapolis Colts look to keep their playoff hopes alive, up next for them is a home matchup with the San Francisco ...

The Steelers and Colts aren't created equally here, though. Assuming the Colts re-sign Jones after his injury, he'll be ...

San Francisco 49ers quarterback Brock Purdy joins NFL Network's "Inside Training Camp Live" to provide a state of the team's ...

Whether it's John Harbaugh complaining about an overturned TD or Andy Reid's pushback on the tush push, the NFL pays ...

QB Mac Jones could draw major offseason trade interest after impressing in relief of Brock Purdy, according to an NFL insider ...

Explore several underrated defenses poised to deliver in favorable Week 16 matchups. Every fantasy football manager knows the stress of weekly lineup decisions, but defense and special teams (D/ST) ...

The Indianapolis Colts seemed to find their QB for at least the near future in Daniel Jones, who was having arguably the best ...

The Indianapolis Colts seemed fully committed to Daniel Jones after his impressive revival under Shane Steichen. Now, with ...

All odds referenced are courtesy of BetMGM as of publish time.

The Philadelphia Eagles are still hopeful of winning a second consecutive Super Bowl this year, but changes may be coming either way for 2026. Jeremy ...