Affiliations 1. Institute of Argumentation, Linguistics and Semiotics , USI-Università della Svizzera italiana , , Authors Greco S 1 Jermini-Martinez Soria C 1 Authors Greco S 1 Jermini-Martinez Soria ...
Abstract While exploring strategies to control blood glucose concentrations in diabetes, we identified so-called molecular glues D223 and D927 that promote glucose uptake in the absence of insulin.
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details. Free full text in Europe PMC Share this article Share with emailShare ...
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details. Free full text in Europe PMC Share this article Share with emailShare ...
Abstract This study identifies a novel function of Sortilin-related receptor with A-type repeats (SORLA), traditionally linked to Alzheimer's Disease (AD) as a high-risk gene and associated with ...
A preprint is a complete scientific manuscript that an author uploads on a public server for free viewing. Initially it is posted without peer review, but may acquire feedback or reviews as a preprint ...
Antibody-based therapeutics must not undergo chemical modifications that would impair their efficacy or hinder their developability. A commonly used technique to de-risk lead biotherapeutic candidates ...
Despite significant advancements in recent decades, gaining a comprehensive understanding of brain computations remains a significant challenge in neuroscience. Using computational models is crucial ...
This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details. Free full text in Europe PMC Share this article Share with emailShare ...
The properties of mRNA lipid nanoparticles (mRNA-LNPs), including size, empty particles, morphology, storage stability, and transfection potency, are critically dependent on the preparation methods.
Salinity is one of the most severe abiotic stresses that adversely affect plant growth and agricultural productivity. The plant Na + /H + antiporter Salt Overly Sensitive 1 (SOS1) located in the ...