Background Gastric cancer (GC) ranks among the most prevalent lethal tumours globally. Cancer-associated fibroblasts (CAFs) are pivotal in creating an immunosuppressive tumour microenvironment (TME) ...
Background With population ageing, elderly patients account for a growing proportion of hepatic surgery recipients. Hepatic ischaemia-reperfusion injury (HIRI) is a major cause of postoperative liver ...
Background For large non-pedunculated rectal polyps, en bloc resection via endoscopic submucosal dissection (ESD) is typically recommended due to presumed higher risk of submucosal invasive cancer ...
After innumerable negative or inconclusive studies to find a pharmacological prophylactic for post-ERCP pancreatitis (PEP), two randomised trials in the USA1 and China2 ushered a new era of ...
Background The combination of atezolizumab and bevacizumab (ATZ/BVZ) therapy has significantly advanced therapeutic approaches for hepatocellular carcinoma (HCC). However, less than 30% of patients ...
We read with great interest the article by Adams et al in *Gut* on the development and validation of the Admission Model for Intensification of Therapy in Acute Severe Colitis (ADMIT-ASC) score to ...
a Department of Molecular and Cellular Pathology, University of Dundee, Dundee, UK, b School of Applied Science, South Bank University, London, UK Dr M J Hopkins, MRC Microbiology and Gut Biology ...
Background Existing scales for assessing faecal incontinence have not been validated against clinical assessment, or with regard to reproducibility. They also fail to take into account faecal urgency, ...
BACKGROUND AND AIMS Controversy surrounds the risk of colorectal cancer (CRC) in ulcerative colitis (UC). Many studies have investigated this risk and reported widely varying rates. METHODS A ...
Correspondence to Professor Shiv Kumar Sarin, Hepatology, Institute of Liver and Biliary Sciences, New Delhi, Delhi 110070, India; shivsarin{at}gmail.com Objectives Beta-blockers and endoscopic ...
1 Department of Paediatrics, University of Naples Federico II, Naples, Italy and European Laboratory of Food Induced Disease (ELFID), Naples, Italy Background and aims: The genetic load in coeliac ...
Background—Gut translocation of bacteria has been shown in both animal and human studies. Evidence from animal studies that links bacterial translocation to the development of postoperative sepsis and ...
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