Background Lupus nephritis (LN) is the most serious complication of SLE. Interstitial fibrosis is the dominant pathological ...

Objective Peer mentoring has been shown to be an effective intervention for chronic conditions with evidence to suggest that ...

Objective SLE affects multiple organs and is associated with increased mortality and organ damage. While treatment recommendations for non-renal SLE stratify by disease activity, no standard approach ...

Objective To investigate second kidney biopsy as predictor of end-stage kidney disease (ESKD) in active lupus nephritis (LN). Methods Patients with biopsy-proven LN (International Society of ...

SLE is a serious, debilitating autoimmune disease that affects various organs and body systems. Of all the heterogeneous autoimmune diseases, SLE is perhaps the most heterogeneous. Patients with SLE, ...

Objective Macrophage activation syndrome (MAS), a subtype of secondary haemophagocytic lymphohistiocytosis (HLH), is a rare ...

Objective To assess the economic burden of patients with SLE by disease severity in the USA 1 year before and after diagnosis. Methods Patients aged ≥18 years with a first SLE diagnosis (index date) ...

Objective To evaluate frequency, severity and costs of flares in US patients with newly diagnosed SLE. Methods Adults diagnosed with SLE between January 2005 and December 2014 were identified from US ...

Objective To identify new genetic variants associated with SLE in Taiwan and establish polygenic risk score (PRS) models to improve the early diagnostic accuracy of SLE. Methods The study enrolled ...

Objective Glomerular immune complex deposition plays a central role in lupus nephritis (LN), but the prognostic relevance of individual immunoglobulin components remains unclear. This study aimed to ...

Background SLE is a chronic autoimmune disease with heterogeneous manifestations and variable outcomes. Geographic factors such as rural residence may influence disease severity, access to care and ...

Objective Antiphospholipid syndrome (APS) is a rare autoimmune condition characterised by thrombosis and/or pregnancy morbidity in the presence of antiphospholipid antibodies. Despite the publication ...