Pulmonary embolism (PE) remains challenging to diagnose and, in particular, to risk stratify. Many patients with low-risk PE ...
Background Antimicrobial resistance (AMR) is a global threat for people with chronic lung infection; however, international ...
Macrolide therapy is an established and effective treatment for selected patients with chronic obstructive airways diseases who experience frequent exacerbations despite optimal therapy. Randomised ...
Coordinated bronchial, vascular and lobation abnormalities associated with right upper lobe agenesis
An 81-year-old woman with a history of diabetes mellitus and angina underwent chest CT after an abnormal chest radiograph suggesting a right pulmonary vascular abnormality. She had no respiratory ...
Diarrhoea is the primary cause of nintedanib discontinuation in idiopathic pulmonary fibrosis. We investigated predictors in 100 prospective patients; 46% experienced diarrhoea, defined as common ...
Cystic fibrosis (CF) has been transformed by therapies that correct and potentiate the cystic fibrosis transmembrane conductance regulator (CFTR) protein.1 Highly effective CFTR modulator therapies ...
Background In most chronic airway diseases, identifying phenotypes has advanced clinical practice and research. However, no such phenotypes exist for paediatric bronchiectasis. We therefore sought to ...
Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) are a significant cause of morbidity and mortality among patients in the intensive care unit (ICU). Early antibiotic therapy ...
A 65-year-old male, who does not smoke, with a history of right lower lobectomy for carcinoid tumour 15 years prior, was referred for persistent, unexplained cough over 12 months. This was ...
Background Disease modifying therapies for progressive fibrotic interstitial lung diseases (F-ILDs) slow physiological decline but have not consistently shown to improve patient-reported symptoms or ...
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Establishing the top 10 research priorities for lung volume reduction treatment for people with COPD
Lung volume reduction procedures are an established evidence-based aspect of chronic obstructive pulmonary disease (COPD) care. We conducted a research prioritisation exercise involving people with ...
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