This review uncovers how aging reshapes immunoglobulins, particularly IgG, IgM, and IgA, driving inflammation, cellular senescence, and tissue degeneration. By dissecting B-cell dysfunction, ...
CXC chemokine receptor 4 (CXCR4) is a receptor overexpressed in several tumor types and associated with tumor aggressiveness and risk of metastasis, resistance and recurrence. A novel PET ...
Final data analysis from the Dimerix collaboration with PARASOL reinforces the company’s proteinuria-based endpoints in its phase III ACTION3 trial of lead drug DMX-200 in rare kidney disease Focal ...
CHS-114, an anti-CCR8 cytolytic antibody, will also be featured in SITC’s upcoming webinar series “Targets for Cancer IO: A Deep Dive” on October 22, 2025 –REDWOOD CITY, Calif., Oct. 03, 2025 (GLOBE ...
New research based on adults who were cured of HIV after stem cell transplants may offer hope to ultimately have a global impact on HIV care. A total of 10 individuals with HIV have been cured to date ...
In the march of metastasis, a molecular trail of crumbs guides some cancer cells from the primary tumor to establish new colonies within the body. Blocking the cells' ability to follow the trail might ...
Inflammation is a significant risk factor and contributor to the development of cardiovascular disease by driving adaptive and maladaptive responses to cardiac injury. Macrophages are the most ...
Divison of Neuroscience & Ageing Biology, CSIR-Central Drug Research Institute, Lucknow 226031, India ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. T lymphocyte migration triggered by chemokine ...
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