A reduction in urinary citrate levels may be the mechanism underlying the higher incidence of kidney stones in patients taking PPIs, according to investigators. Individuals who use proton pump ...

Ammonia and Kidney Failure Study implicates an inability of a CKD patient's kidneys to excrete the daily acid load. Lower urinary ammonia excretion, a marker of an impaired ability of the kidneys to ...

Acute renal failure is defined as a rapid decrease in the glomerular filtration rate, occurring over a period of minutes to days. Because the rate of production of metabolic waste exceeds the rate of ...

The most common cause of RI in MM is cast nephropathy, which may be seen in up to 30% of patients; 9 other causes of RI include monoclonal immunoglobulin (Ig) deposition disease and amyloidosis. It ...

Certain textbooks/references suggest a maximum dose of allopurinol (Xyloprim, Lopurin) in patients with renal insufficiency. Presumably, this is because of renal excretion of the metabolite, ...

Nuts, particularly almonds, cashews, and peanuts, are rich in oxalates, which can contribute to kidney stone formation if consumed in large amounts. While nuts are otherwise healthy, moderation is key ...

Nephrotoxicity, the major complication of long-term therapy with amphotericin B, is attributed to drug-induced renal vasoconstriction plus a direct toxic action on renal tubules. Hypokalemia and ...

Compared to group I GBCAs, group II GBCAs appear safe for use in patients with severe kidney disease. In a recent analysis, the risk of NSF in patients with stage 4 or 5 CKD was less than 0.07% with ...

Women with renal disease, which is also known as kidney disease, are at a significantly increased risk of complications during pregnancy, despite advances in healthcare to reduce these outcomes. The ...