HOUSTON, TX – FEBRUARY 05: Lady Gaga performs during the Pepsi Zero Sugar Super Bowl 51 Halftime Show at NRG Stadium ... a setlist that included hits like “Let’s Go Crazy” and “Baby I’m a Star,” as ...

Vincent Gaynor remembers, almost to the minute, when he realized his part in birthing the breakthrough gene therapy Zolgensma ...

The crew of the Cutter Haddock intercepted a 30-foot panga-style vessel 21 miles off Point Loma, the Coast Guard said. The ...

A San Diego migrant shelter is closing and laying off 115 employees after not receiving any new asylum seekers since ...

Nathan East will receive the Lifetime Achievement Award. Other multiple nominees this year include The Neigborhood Kids, ...

A man from Shafter, California was arrested in San Diego County earlier this week on suspicion of child sexual assault, ...

For those drawn to the nostalgia of times before, here’s a collection of photos taken in the San Diego region during the 30s and 40s.

SAN DIEGO (FOX 5/KUSI) — San Diego is expected to get hit by its first major storm of the year this week following the single slowest start to the region’s typical “rainy season” in ...

President Donald Trump froze the federal funding that allowed resettlement agencies to support newly arrived refugees. Some ...

Daley’s school has one of the food pantries that’s supplied twice a month by Feeding San Diego. The no-profit’s School Pantry Program feeds roughly 11,500 households every month.

That's the question San Diego's Fire and Rescue Department had to answer before The San Diego City Council’s Public Safety Committee meeting. Both Mayor Todd Gloria and Fire Chief Robert Logan ...

A U.S. Navy electronic-warfare aircraft crashed into San Diego Bay near Naval Air Station North Island on Wednesday, sending two service members to the hospital. The Navy confirmed there were two ...