Colts injury report for Week 16 as Christian McCaffrey, Trent Williams and Ricky Pearsall are among six who missed practice ...

San Francisco 49ers coach Kyle Shanahan and running back Christian McCaffrey share their impressions of Indianapolis Colts ...

San Francisco 49ers TE George Kittle, RB Christian McCaffrey, and DL Keion White discussed the energy inside the locker room, ...

The San Francisco 49ers might have a new face at linebacker when they visit the Indianapolis Colts in Week 16.

Colts’ Jonathan Taylor; Ricky Pearsall Jr. doesn’t practice but Kyle Shanahan likes his chances to play Monday.

San Francisco 49ers wide receiver Ricky Pearsall has missed the team's first practice of the week due to knee and ankle ...

San Francisco 49ers head coach Kyle Shanahan highlighted Indianapolis' run defense, reflected on overcoming injuries, and ...

Kyle Shanahan says wide receiver Brandon Aiyuk has been 'extremely distant' since his ACL/MCL injuries last season.

Brandon Aiyuk has not played this season after suffering a torn ACL and MCL in Week 7 of the 2024 campaign, and San Francisco ...

The San Francisco 49ers have a big Week 16 Monday Night Football clash against the Colts, and here are bold predictions.

Maurice Moton of Bleacher Report isn’t sold on the excellent offensive stretch from the 49ers, citing the opponents.