BMJ Evidence-Based Medicine (BMJ EBM) publishes original evidence-based research, insights and opinions on what matters for health care. We focus on the tools, methods, and concepts that are basic and ...

Objective To assess evidence of overall survival (OS) benefits of cancer drugs listed in China’s National Reimbursement Drug List (NRDL), the guiding standard for public insurance coverage of drugs ...

Introduction: High-quality randomised controlled trials (RCTs) provide the most reliable evidence on the comparative efficacy of new medicines. However, non-randomised studies (NRS) are increasingly ...

Correspondence to Professor John Brodersen, Centre of Research & Education in General Practice, Department of Public Health, University of Copenhagen, Faculty of Health Sciences, Copenhagen 1014, ...

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Objectives The objective of our study was to assess the benefits and harms of tramadol vs placebo in adults with chronic pain. Design The research method was a systematic review of randomised clinical ...

Objective This study aims to comprehensively review the literature on the use of speech biomarkers in disease diagnosis and monitoring, focusing on recording protocols, speech tasks, speech features ...

Health technology assessment in India in the next decade: reflections on a vision for its path to maturity and impact ...

Background Misleading information about medical products on social media may cause overuse. Objectives Explore interventions targeting the problem of misleading medical information and marketing on ...

Background In November 2017, the Food and Drug Administration (FDA) approved a version of a second-generation antipsychotic, aripiprazole, embedded with a sensor (Abilify MyCite). Objective To ...

Objective To investigate the efficacy and safety of open-label placebos (OLP) in premenstrual syndrome (PMS). Design Randomised controlled trial. Setting Switzerland, 2018–2020. Participants 150 women ...

Objectives To investigate the relationship between alcohol consumption and dementia. Design Prospective cohort and case–control analyses combined with linear and non-linear Mendelian randomisation.