Childhood obesity remains a pressing global health challenge, yet the impact of dynamic adiposity changes during active developmental window retains poorly understood. Leveraging longitudinal data ...
Transcranial focused ultrasound (tFUS) can modulate activity in deep brain regions non-invasively, yet its effects remain variable and incompletely understood. Because sonication deposits mechanical ...
This important study shows that neural responses to visual input during active vision are more closely aligned with self-generated eye movements than with fixation onset. The evidence for neural ...
This study presents valuable findings regarding the role of the P2X7 receptor in retinoic acid signaling-mediated retinal remodeling following photoreceptor degeneration. However, the evidence ...
Science is better when we publish according to our values! Most publishing models act as a barrier, rather than a medium, between authors and audiences; eLife feels like the opposite.
Instituut-Lorentz, Universiteit Leiden, Netherlands; Physics Department, College of Sciences, Koç University, Turkiye; ...
After publication we discovered we inadvertently used incorrect overlapping images representing different experimental conditions. Specifically, errors were introduced into some of fluorescence ...
Proteolysis-targeting chimeras (PROTACs) enable the selective and sub-stoichiometric elimination of pathological proteins, yet only two E3 ligases are routinely used for this purpose. Here, we expand ...
This valuable manuscript uses mathematical modeling to address the synchrony of the vertebrate segmentation clock with the developmental processes. The authors use convincing arguments to support the ...
This study provides important computational insights into the dynamics of PROTAC-induced degradation complexes, offering a convincing demonstration that differences in degradation efficacy can be ...
The autobiographical memory deficits seen in aphantasia are reflected by altered activation and connectivity patterns of the hippocampus and occipital cortex, corroborating the strong link between ...
This important study advances our understanding of the mechanisms underlying chromatin-mediated gene regulation by SET DOMAIN-CONTAINING PROTEIN 7 (SDG7). The evidence supporting the author's claims – ...