Patients with immune-mediated inflammatory diseases (IMIDs) are at increased risk of herpes zoster (HZ), particularly those ...
Objectives The additional impact of coexisting Sjögren’s syndrome (SS) on cardiac involvement in patients with systemic lupus ...
Moreover, as some clinical trials have excluded them, the efficacy of some immunosuppressants for this subset of patients has not been strictly confirmed. In this study, we aimed to investigate the ...
Background SLE features aberrant type I interferon production, with the stimulator of interferon genes (STING) pathway acting as a key upstream driver. However, its expression patterns in patients ...
Objective To identify factors associated with individual Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SDI) accrual items in 1385 patients from the ...
1702 Patients enrolled in the accelerating medicines partnership (AMP) RA/SLE network with isolated renal disease report minimal quality of life impairment on PROMIS-29 compared to patients with ...
Objectives Activation of endosomal toll-like receptor (TLR)7 or TLR9 has been proposed as a critical step for the initiation and development of SLE. Traditional spontaneous lupus models normally ...
Background Systemic lupus erythematosus (SLE) is a chronic autoimmune disease influenced by multiple factors. Growing evidence suggests that adverse childhood experiences (ACEs) and post-traumatic ...
Objectives Investigate the role of antiphospholipid antibodies (aPL) in determining subclinical microvascular alterations in patients with primary antiphospholipid syndrome (PAPS) and antiphospholipid ...
Objective Fatigue is a common, multifaceted symptom in SLE which is difficult to treat. There has been a lack of broadly accepted SLE-specific assessment tools for fatigue. This study assessed the ...
Objective To characterise the safety and efficacy of anifrolumab in active lupus nephritis (LN) through year 2 of the phase II randomised, double-blind Treatment of Uncontrolled Lupus via the ...
22 Historical aspects of B-cell depletion in SLE (8 October, 2025) ...
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